[Complex immunization of animals against anthrax and brucellosis].
نویسندگان
چکیده
منابع مشابه
Proposal: “Development of Bivalent Live Recombinant Vaccine Against Brucellosis and Anthrax” Project Manager: Anatoly N. Noskov, MD Objective: Development of a live bivalent vaccine against brucellosis and anthrax for veterinary use. Reviewer: Matthew Meselson
This is a proposal to modify vaccine strains of B. anthracis (strains ST1 and Sterne) by introducing into them plasmids that code for fusion proteins intended to confer immunity both to anthrax and to brucellosis. The resulting live bivalent vaccine would then replace the live monovalent anthrax vaccines currently in use. DESCRIPTION Brucellosis is a debilitating although seldom lethal bacteria...
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Objective(s): Brucellosis is a common infectious disease among animals and humans. While subunit vaccines could be used as an efficient strategy against pathogens, they usually seem to be less immunogenic than live or killed vaccines. However, the use of a suitable adjuvant accompanied by subunit vaccines can be a good alternative to enhance the immune response.Materials and Methods: To find a ...
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Received: 13 January, 2009 Accepted: 4 Feb, 2009 Abstract Background & Aims : Brucellosis is a widespread, economically devastating and highly infectious zoonosis. Mass immunization has become a favorite strategy to control of disease .in, this study, we tried to estimate marginal effectiveness of livestock immunization program in West-Azerbayjan province. Materials &Methods : Epidemiolog...
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Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation...
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Human vaccination with BioThrax requires six injections followed by annual boosters. This makes it difficult for the compliance of the immunization program and underscores the need for development of a new and optimized vaccination protocol. Current research aims to demonstrate the proof of concept to develop a needle-free mucosal immunization protocol using a murine anthrax model. A/J mice wer...
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عنوان ژورنال:
- Veterinariia
دوره 44 7 شماره
صفحات -
تاریخ انتشار 1967